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Connectivity of 3D structures in tissues provides metrics for organ development Organs in the human body have complex networks of fluid-filled tubes and loops. They come in different shapes, and their three-dimensional structures are differently connected to each other, depending on the organ. During the development of an embryo, organs develop their shape and tissue architecture out of a simple group of cells. It has been challenging to understand how shape and the complex tissue network arise during organ development.
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